IVF outcome in females with hypothyroidism with strict control of TSH levels

Hypothyroidism (Low Fertility)

plasma concentrations of estrogens and androgens

  • Deficient LH secretion
  • Reduced libido and anovulation

During IVF & Pregnancy

Strict control of TSH levels


To assess the IVF outcome in infertile females with hypothyroidism after the strict control of TSH levels


  • Duration of study – 6 months
  • Subject – 100 infertile females
    • Group A – 50 females (euthyroid)
    • Group B – 50 females (hypothyroidism)
      • TSH levels > 8 mIU/L in initial infertility work up)
  • Levothyroxine 50 mcg
  • TSH repeated after 7 to 10 days
  • Start of stimulation, before ET and on Beta HCG days.
  • Dose titration according to levels
  • Embryo transfer planned when TSH levels <4 mIU/L



Need to compare pregnancy outcome with poorly controlled group.

Did not study role of TPO

Did not study miscarriage rate



  • Increased risk of infertility
  • Results in IVF failure


Tight Control of TSH levels in Hypothyroid women undergoing IVF leads to similar pregnancy rates as Euthyroid patients

First ever study of this kind to the best of our knowledge

Book an appointment

IVF Pregnancy Cost Calculator

Request For Appointment

Calculate IUI Treatment Cost

Test Tube Baby / IVF Cost Calculator

Failed IVF Treatment Cost Calculator

Surrogacy Enquiry Form

Egg Freezing Cost/Embryo Freezing Cost

Preimplantation genetic diagnosis (PGD)/(PGS) with IVF Cost

Calculate ICSI Treatment Cost

Male Infertility Treatment Cost Calculator

Female Infertility Treatment Cost Calculator